Postdoctoral Researcher - Spatial Omics for Colorectal Cancer Risk Stratification

Position Overview

Located within the Systems Physiology lab at ETH Zurich in Basel, the project focuses on identifying novel prognostic biomarkers for Colorectal Cancer (CRC) through advanced spatial omics technologies and digital pathology. With this collaborative initiative co-led by the University Hospital Basel, the work aims to improve the identification of high-risk Stage II CRC patients, addressing a critical public health challenge.

Key Responsibilities

The successful candidate will:

• Generate and analyze spatial transcriptomics and image datasets related to CRC.
• Identify novel prognostic biomarkers for enhanced risk stratification.
• Translate findings into robust, interpretable models.

Desired Qualifications

• PhD in Computational Biology, Bioinformatics, Cancer Biology, Molecular Biology, Pathology, or a related discipline.
• Strong experience in spatial omics technologies and hands-on data analysis.
• Proficiency in bioinformatics and computational analysis of large-scale biological datasets.
• Solid background in machine learning methods, particularly with neuronal networks or deep learning for image analysis.
• Expertise in digital pathology including image processing and feature extraction from histological datasets.
• Programming skills in R and/or Python.
• Experience in colorectal cancer research is beneficial.
• Able to work independently and collaboratively in a dynamic environment.
• Strong communication, organizational, and problem-solving capabilities.
• Proven track record of scientific publications is an advantage.

Work Environment

The position offers the opportunity to engage in a clinically relevant project that bridges basic research and clinical applications. The successful candidate will benefit from:

• Access to cutting-edge spatial omics technologies and large archival patient cohorts.
• A stimulating research environment at ETH Zurich's D-BSSE and the University Hospital Basel.
• Competitive salary and benefits according to ETH Zurich guidelines.
• Professional development opportunities and support for scientific growth.

Diversity and Inclusion

ETH Zurich is committed to fostering an inclusive culture. The organization values equality of opportunity and nurtures a diverse working and learning environment that respects the rights and dignity of all staff and students.

Institution Overview

ETH Zurich ranks among the world's leading universities in science and technology, recognized for its outstanding education and cutting-edge research. The university cultivates a space that encourages independent thought and inspires excellence, drawing over 30,000 members from more than 120 countries.