Principal Scientist - Liver Diseases

Position Overview

Located in Basel, Switzerland, this full-time position is focused on advancing transformative therapies for patients with chronic diseases, particularly liver diseases, at the Novartis Biomedical Research facility.

Role Responsibilities

In this pivotal role, you will:

• Lead a team of scientists dedicated to preclinical activities for identifying and validating targets and drug candidates, with an emphasis on liver diseases.
• Utilize innovative in vitro/ex vivo models that replicate human disease conditions to identify potential drug candidates.
• Translate therapeutic concepts between preclinical models and patient-focused applications, employing cutting-edge experimental approaches and data science tools.
• Significantly influence the strategic direction of liver research, remaining current with developments in the field.
• Mentor and guide a high-performing team, fostering a collaborative atmosphere while enhancing team members' skills.
• Collaborate effectively in a matrix-based, cross-functional environment across departments within Novartis Biomedical Research.
• Maintain strong external collaborations with academic institutions and manage partnerships.

Key Qualifications

The ideal candidate will possess:

• A PhD/Postdoc in life sciences, including cell or molecular biology or physiology.
• At least 5 years of experience in drug discovery for chronic diseases within an industrial setting, showcasing a range of expertise from target identification to clinical applications.
• An in-depth molecular understanding of physiology and disease pathophysiology, particularly concerning liver diseases, along with expertise in cell-based methods that emulate disease conditions.
• High proficiency in molecular, cellular, and biochemical assay and profiling technologies, including single-cell transcriptomics.
• A robust understanding of data science and experience in utilizing data science tools to analyze complex datasets.
• Proven leadership capabilities, including team management, setting objectives, and fostering individual development.
• Demonstrated ability to work autonomously as well as collaboratively within interdisciplinary teams of biologists, computational scientists, and translational researchers.
• Excellent communication skills, strong organizational abilities, and meticulous attention to detail.

Work Environment

Novartis is dedicated to creating an outstanding and inclusive work environment with diverse teams that reflect the patients and communities we serve. We welcome the opportunity to discuss reasonable accommodations for individuals with medical conditions or disabilities throughout the recruitment process.

Our Commitment

At Novartis, we believe that helping people with diseases and their families requires more than just innovative science; it takes a passionate community. Come and be a part of a collaborative effort that drives breakthroughs to change patients' lives. Together, we can create a brighter future.