PhD Positions in Neurotechnology: Next Generation Non-invasive Neurotechnologies & Brain Therapies

Opportunities in Neurotechnology Research

The Neurotechnology Group led by Prof. Mehmet Fatih Yanik at ETH Zurich is seeking exceptional PhD students to contribute to an innovative project aimed at pioneering non-invasive drug delivery technologies for brain therapies. This project develops a focused ultrasound-mediated platform for targeted drug delivery, which has been documented in scientific literature for its efficiency in delivering therapeutic compounds precisely to brain regions.

Project Overview

The initiative focuses on creating advanced ultrasound technologies and responsive therapeutic carriers, designed to improve the efficacy of drug delivery to the brain. By leveraging a novel two-component ultrasound strategy, the platform aims to optimize the concentration and release of drugs at targeted areas, thereby minimizing systemic side effects. The overarching goal is to bring this technology into clinical practice, enhancing treatment options for various neurological disorders through collaborative efforts with esteemed medical and research institutions.

Key Responsibilities

Engagement in this project involves a range of interdisciplinary activities that may include:

• Development of next-generation focused ultrasound systems
• fMRI-guided treatment planning and targeting
• Optimization of therapeutic dosing and drug delivery
• Creation of closed-loop ultrasound neuromodulation systems
• Design of custom hardware and software solutions
• Conducting electrophysiology and neurophysiology experiments
• Executing rodent and large-animal neuroscience studies
• Translating technology for clinical application
• Partnering with clinicians on first-in-human clinical studies
• Involvement in medical device development and regulatory compliance

Candidate Profile

We are looking for highly motivated and creative individuals with a strong interest in interdisciplinary research. Applicants should have a Master’s degree in relevant fields such as:

• Biomedical Engineering
• Electrical Engineering
• Mechanical Engineering
• Physics
• Neuroscience
• Computer Science
• Chemistry
• Or a closely related field

Ideal candidates will possess:

• An exemplary academic record
• Strong quantitative and analytical skills
• Experimental laboratory experience
• Programming proficiency (Python, MATLAB, C++, or similar)
• A passion for developing novel biomedical technologies
• Strong motivation for translational neuroscience
• Experience with mechanical design and prototyping
• Previous exposure to focused ultrasound, fMRI, or related disciplines

Due to the nature of this project, candidates should be prepared to participate in translational preclinical studies involving animal research.

Research Environment

The Neurotechnology Group at ETH Zurich provides a dynamic research framework, equipped with:

• High-field 7 Tesla MRI capabilities
• Cutting-edge microscopy and electrophysiology infrastructure
• Access to advanced prototyping, microfabrication, and chemical synthesis facilities
• Collaboration opportunities with a network of scientists and clinicians

Commitment to Diversity and Sustainability

ETH Zurich is committed to fostering an inclusive workplace where diversity is valued. We encourage equality of opportunity and maintain a supportive environment for all individuals, promoting a culture of respect and growth. Sustainability is vital to our mission, and we actively pursue initiatives for a climate-neutral future.

Join Us

If you are enthusiastic about making a significant impact within the field of neurotechnology and are eager to collaborate with top-tier professionals, we look forward to the prospect of your contributions to our innovative research environment.