Medical Scientist

Principal Scientist: Immunology & Biologics Discovery

Are you a highly accomplished Immunologist with a track record of leading scientific teams and driving biologics discovery programmes in autoimmune and inflammatory diseases? This position will oversee breakthrough work in inflammation and immunology, playing a central role in shaping therapeutic approaches and developing next-generation biologic therapies.

Working at the forefront of immunology research, you will lead and support multidisciplinary programmes spanning target identification, pharmacology, translational research, and therapeutic antibody development. You will combine hands-on scientific expertise with leadership, helping to advance novel biologic therapies from early discovery through preclinical development.

Key Responsibilities

• Lead and mentor a team of laboratory-based scientists, supporting both scientific delivery and career development
• Design, oversee, and interpret complex in vitro and in vivo pharmacology studies
• Drive the development of novel therapeutic strategies within autoimmune and inflammatory disease programmes
• Design and optimise immune-based assays to support target validation and antibody discovery
• Collaborate closely with experts across immunology, translational medicine, protein engineering, biomarkers, and clinical development
• Work with CRO partners to coordinate efficacy and pharmacology studies
• Develop and implement endpoint and mechanism-of-action studies, including ex vivo immune profiling
• Identify project risks, influence programme strategy, and support key decision-making discussions
• Contribute to scientific publications, patents, regulatory documentation, and due diligence activities
• Represent research programmes through conference presentations and external scientific collaborations

Essential Skills and Requirements

• PhD in Immunology, Life Sciences, or a related discipline
• Minimum 5 years' experience within immunology, inflammation research, or biologics drug discovery
• Strong understanding of autoimmune disease biology and immune system mechanisms
• Proven experience leading scientific projects and mentoring research teams
• Expertise across in vitro pharmacology, assay development, and immune profiling
• Experience supporting biologics, antibody, or therapeutic development programmes
• Strong publication record with peer-reviewed scientific contributions
• Excellent communication, stakeholder management, and leadership skills
• Biotechnology or pharmaceutical industry experience
• In vivo pharmacology programme leadership
• Translational research and target validation experience
• Experience working with CROs and external research partners
• Contribution to IND-enabling studies, patent applications, or due diligence activities
• Exposure to strategic portfolio or pipeline decision-making