Reserach Technician: Molecular technology development

Join Our Innovative Research Team

The Laboratory for Biological Engineering at ETH Zurich, under the guidance of Prof. Randall J Platt, is focused on the development of cutting-edge genome engineering technologies to address both fundamental scientific questions and pressing challenges in health. We are eager to welcome a talented and dedicated research technician to our multidisciplinary team in Basel, Switzerland.

Key Responsibilities

The selected individual will collaborate closely with laboratory scientists on various ongoing projects, with a focus on:

• Molecular cloning techniques (PCR, classic restriction enzyme cloning, Golden-Gate Assembly, and Gibson assembly)
• Preparation of plasmid DNA from E. coli
• Maintenance and transfection of standard mammalian cell lines
• Flow cytometry
• Production and purification of lentivirus and adeno-associated virus
• Titration of viruses using functional titration, qPCR, or droplet digital PCR
• Preparation of DNA libraries for high-throughput sequencing
• Other common tasks in molecular and cellular biology

Additional responsibilities may include working with mouse models, focusing on husbandry, injections, tissue dissection, and cell or nuclei isolation.

Qualifications

The ideal candidate will possess:

• A completed apprenticeship as a biology laboratory technician or a Master's degree (or equivalent) in Molecular Biotechnology, Biochemistry, Molecular Medicine, Structural Biology, Molecular and Cellular Biology, or a related field.
• Effective communication skills in English, both written and oral, in a diverse and international environment.
• A genuine passion for science, technology, collaboration, and communication, alongside a strong motivation for teamwork in a multi-disciplinary context.
• Extensive experience in contemporary molecular and cellular biology methods, as outlined in the responsibilities.
• Proficiency in Excel, PowerPoint, and at least one cloning (e.g., Geneious) and plotting software (e.g., Prism).
• Experience with illustration software (e.g., Adobe Illustrator, BioRender) and mouse models is a plus but not mandatory.

Working Environment

This position is situated within the Department of Biosystems Science and Engineering (D-BSSE) at ETH Zurich, a hub of interdisciplinary research specializing in systems and synthetic biology, bioinformatics, and engineering sciences. The D-BSSE is strategically located in Basel, a vibrant international city ideally positioned between the Swiss Alps, Black Forest, and easily accessible to cultural, natural, and adventurous pursuits throughout Europe.

Additional Information

For those interested in learning more about our department and research endeavors, further information can be found on our official website. We look forward to engaging with individuals who are eager to contribute to our exciting projects and be part of our dynamic team.