Bioanalytical Scientist / Research Associate (Large Molecule Bioanalysis)

Join Our Innovative Team

Ridgeline Discovery, a leading Discovery Engine fueled by Versant Ventures, is at the forefront of creating and operating groundbreaking biotech companies across Europe. With a dynamic team of over 50 seasoned drug discovery and industry professionals, Ridgeline has successfully established multiple companies backed by substantial funding through Series B, IPO, and trade sale exits.

Key Responsibilities

Bioanalytical Assay Development & Validation

• Design, develop, optimize, qualify, and validate bioanalytical methods for large molecule therapeutics.
• Establish, develop, and perform immunoassays, including ligand-binding assays (LBAs) such as ELISA, MSD/ECL, Gyrolab, and related platforms.
• Lead assay troubleshooting, root-cause investigations, and implementation of corrective actions.
• Generate robust bioanalytical data to support pharmacokinetic (PK), immunogenicity (ADA/NAb), and biomarker assessments.
• Ensure assays are fit-for-purpose and compliant with applicable regulatory guidance and industry best practices.
• Contribute to the scientific interpretation of bioanalytical data and preparation of study reports.
• Analyze, document, and communicate experimental results clearly and accurately.
• Maintain relevant laboratory documentation, assay procedures, and validation records.

CRO Management & External Collaboration

• Serve as the bioanalytical point of contact for external CRO partners.
• Coordinate assay transfer, method development, qualification, validation, and sample analysis activities conducted by CROs.
• Review study protocols, validation plans, data packages, and final reports.
• Monitor study timelines, deliverables, data quality, and regulatory compliance.
• Collaborate with internal project teams to ensure timely delivery of bioanalytical support across programs.
• Provide scientific oversight of outsourced bioanalytical activities and contribute to vendor selection and performance evaluation.

Qualifications

Education

• MSc in Biology, Biochemistry, Biotechnology, Pharmaceutical Sciences, Immunology, or a related field with relevant industry experience; or PhD in a relevant scientific discipline.

Experience

• 3+ years (Research Associate) or 5+ years (Scientist) of relevant experience in bioanalysis of large molecule therapeutics within biotechnology, pharmaceutical, or contract research laboratory environments.
• Proven hands-on experience developing, qualifying, validating, overseeing, and troubleshooting immunoassays.
• Experience supporting pharmacokinetic, immunogenicity, and biomarker bioanalysis programs.
• Experience managing outsourced bioanalytical activities and working effectively with CROs.

Technical Skills

• Strong expertise in ligand-binding assays and immunoassay platforms (ELISA, MSD/ECL, Gyrolab, or equivalent).
• Familiarity with regulatory expectations and guidance for bioanalytical method validation.
• Strong data analysis, interpretation, and scientific reporting skills.
• Experience working in GxP-regulated environments is an advantage.
• Experience with MS applications for complex therapeutic modalities is considered a plus.

Personal Attributes

• Hands-on, proactive, and solution-oriented scientist.
• Strong troubleshooting and problem-solving capabilities.
• Excellent organizational and project coordination skills.
• Strong communication skills and the ability to collaborate effectively across internal and external teams.
• Capable of managing multiple priorities in a dynamic environment.